I'm a guitarist so I'll stick with that to start things off:
Favorite: there are so many to choose from, but I've always liked Steve Howe's chorused/flanged tone from Starship Trooper
Also, that really liquidy, smooth lead tone that John McLaughlin gets with his new Godin guitars.
Least Favorite: 60's wah tone used by Cream-era Clapton and early Keith Richards (not sure what wah they were using but it's..painful
Also, Jerry Garcia's 70's strat tone is pretty harsh.






