Mig 50 on clean channel, I (the "bassman" channel, cause fuck bright "plexi" channel II), everything dimed, volume wherever, cause its all clean, presence rolled back to about 3-4.
Dirt pedals and guit tone knobs do the tone shaping.
I used to fuck with eq so much on other amps with graphic and parametric and blah, blah, blah. Then I just decided, "fuck it". Best tone I've ever had.